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1

ChemInform Abstract: Anthracyclines: Selected New Developments.

M. Binaschi, M. Bigioni, A. Cipollone, C. Rossi, C. Goso, C. A. Maggi, G. Capranico, F. Animati

Journal:

Year:

2002

File:

PDF, 22 KB

2002

2

Synthesis, Biological Evaluation, and Molecular Modeling Studies of Rebeccamycin Analogues Modified in the Carbohydrate Moiety

Fabio Animati, Marco Berettoni, Mario Bigioni, Monica Binaschi, Patrizia Felicetti, Lorenzo Gontrani, Ottaviano Incani, Andrea Madami, Edith Monteagudo, Lauso Olivieri, Stefano Resta, Cristina Rossi,

Journal:

Year:

2008

Language:

english

File:

PDF, 657 KB

english, 2008

3

Nuclear factor-κB, induced in human carcinoma cell line A2780 by the new anthracycline men 10755, is devoid of transcriptional activity

Grazia Camarda, Monica Binaschi, Carlo A. Maggi, Cristina Goso

Journal:

International Journal of Cancer

Year:

2002

Language:

english

File:

PDF, 552 KB

english, 2002

4

CD137 and CD137 ligand constitutively coexpressed on human T and B leukemia cells signal proliferation and survival

Carla Palma, Monica Binaschi, Mario Bigioni, Carlo Alberto Maggi, Cristina Goso

Journal:

International Journal of Cancer

Year:

2004

Language:

english

File:

PDF, 572 KB

english, 2004

5

Antitumor activity of delimotecan against human metastatic melanoma: Pharmacokinetics and molecular determinants

Mario Bigioni, Massimo Parlani, Alessandro Bressan, Daniela Bellarosa, Licia Rivoltini, Fabio Animati, Attilio Crea, Rossana Bugianesi, Carlo Alberto Maggi, Stefano Manzini, Monica Binaschi

Journal:

International Journal of Cancer

Year:

2009

Language:

english

File:

PDF, 467 KB

english, 2009

6

Comparison of dna cleavage induced by etoposide and doxorubicin in two human small-cell lung cancer lines with different sensitivities to topoisomerase ii inhibitors

Monica Binaschi, Giovanni Capranico, Paola De Isabella, Mariangela Mariani, Rosanna Supino, Stella Tinelli, Franco Zunino

Journal:

International Journal of Cancer

Year:

1990

Language:

english

File:

PDF, 653 KB

english, 1990

7

Relationships among tumor responsiveness, cell sensitivity, doxorubicin cellular pharmacokinetics and drug-induced DNA alterations in two human small-cell lung cancer xenografts

G. Pratesi, G. Capranico, M. Binaschi, P. De Isabella, S. Pilotti, R. Supino, F. Zunino

Journal:

International Journal of Cancer

Year:

1990

Language:

english

File:

PDF, 771 KB

english, 1990

8

A study of cross-resistance pattern and expression of molecular markers of multidrug resistance in a human small-cell lung-cancer cell line selected with doxorubicin

Rosanna Supino, Monica Binaschi, Giovanni Capranico, Romolo A. Gambetta, Elena Sala, Franco Zunino, Ennio Prosperi

Journal:

International Journal of Cancer

Year:

1993

Language:

english

File:

PDF, 920 KB

english, 1993

9

MRP gene overexpression in a human doxorubicin-resistant SCLC cell line: Alterations in cellular pharmacokinetics and in pattern of cross-resistance

Monica Binaschi, Rosanna Supino, Romolo A. Gambetta, Giuseppe Giaccone, Ennio Prosperi, Giovanni Capranico, Ignazio Catalog, Franco Zunino

Journal:

International Journal of Cancer

Year:

1995

Language:

english

File:

PDF, 697 KB

english, 1995

10

Alkyl piperidine and piperazine hydroxamic acids as HDAC inhibitors

Cristina Rossi, Marina Porcelloni, Piero D’Andrea, Christopher I. Fincham, Alessandro Ettorre, Sandro Mauro, Antonella Squarcia, Mario Bigioni, Massimo Parlani, Federica Nardelli, Monica Binaschi, Car

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2011

Language:

english

File:

PDF, 523 KB

english, 2011

11

Novel anthracycline oligosaccharides: influence of chemical modifications of the carbohydrate moiety on biological activity

A Cipollone, M Berettoni, M Bigioni, M Binaschi, C Cermele, E Monteagudo, L Olivieri, D Palomba, F Animati, C Goso, C.A Maggi

Journal:

Bioorganic & Medicinal Chemistry

Year:

2002

Language:

english

File:

PDF, 290 KB

english, 2002

12

Antitumour effect of combination treatment with Sabarubicin (MEN 10755) and cis-platin (DDP) in human lung tumour xenograft

M. Bigioni, A. Benzo, C. Irrissuto, G. Lopez, B. Curatella, C. A. Maggi, S. Manzini, A. Crea, S. Caroli, F. Cubadda, M. Binaschi

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2008

Language:

english

File:

PDF, 398 KB

english, 2008

13

Amisulpride in the short-term treatment of depressive and physical symptoms in cancer patients during chemotherapies

Riccardo Torta, Carlotta Berra, Luca Binaschi, Roberto Borio

Journal:

Supportive Care in Cancer

Year:

2007

Language:

english

File:

PDF, 217 KB

english, 2007

14

Depression in lung cancer patients: is the HADS an effective screening tool?

Lorys Castelli, Luca Binaschi, Paola Caldera, Riccardo Torta

Journal:

Supportive Care in Cancer

Year:

2009

Language:

english

File:

PDF, 97 KB

english, 2009

15

Fast screening of depression in cancer patients: the effectiveness of the HADS

L. CASTELLI, L. BINASCHI, P. CALDERA, A. MUSSA, R. TORTA

Journal:

European Journal of Cancer Care

Year:

2011

Language:

english

File:

PDF, 75 KB

english, 2011

16

Kainate seizures increase nociceptin/orphanin FQ release in the rat hippocampus and thalamus: a microdialysis study

Liliana Carmona Aparicio, Sanzio Candeletti, Anna Binaschi, Manuela Mazzuferi, Simona Mantovani, Manuela Di Benedetto, Daniela Landuzzi, Giuseppe Lopetuso, Patrizia Romualdi, Michele Simonato

Journal:

Journal of Neurochemistry

Year:

2004

Language:

english

File:

PDF, 258 KB

english, 2004

17

Mechanism of action of DNA topoisomerase inhibitors

Monica Binaschi, Franco Zunino, Giovanni Capranico

Journal:

Year:

1995

Language:

english

File:

PDF, 981 KB

english, 1995

18

4-N-Hydroxy-4-[1-(sulfonyl)piperidin-4-yl]-butyramides as HDAC inhibitors

Cristina Rossi, Christopher I. Fincham, Piero D’Andrea, Marina Porcelloni, Alessandro Ettorre, Sandro Mauro, Mario Bigioni, Monica Binaschi, Carlo A. Maggi, Federica Nardelli, Massimo Parlani, Daniela

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2011

Language:

english

File:

PDF, 411 KB

english, 2011

19

Involvement of nitric oxide in both central and peripheral haemodynamic effect of d/l-nebivolol and its enantiomers in rats

Giuseppe Sacco, Stefano Evangelista, Marco Criscuoli, Cristina Goso, Mario Bigioni, Monica Binaschi, Stefano Manzini, Carlo Alberto Maggi

Journal:

European Journal of Pharmacology

Year:

2005

Language:

english

File:

PDF, 184 KB

english, 2005

20

DNA sequence selectivity of topoisomerases and topoisomerase poisons

Giovanni Capranico, Monica Binaschi

Journal:

Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression

Year:

1998

Language:

english

File:

PDF, 176 KB

english, 1998

21

Synthesis and biological evaluation of rebeccamycin analogues modified at the imide moiety

Fabio Animati, Marco Berettoni, Mario Bigioni, Monica Binaschi, Amalia Cipollone, Clelia Irrissuto, Federica Nardelli, Lauso Olivieri

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2012

Language:

english

File:

PDF, 528 KB

english, 2012

22

Set-up of a new series of HDAC inhibitors: the 5,11-dihydrodibenzo[b,e]azepin-6-ones as privileged structures

Mario Bigioni, Alessandro Ettorre, Patrizia Felicetti, Sandro Mauro, Cristina Rossi, Carlo Alberto Maggi, Elena Marastoni, Monica Binaschi, Massimo Parlani, Daniela Fattori

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2012

Language:

english

File:

PDF, 460 KB

english, 2012

23

36 - New antidepressants in oncological clinical practice: data from a single-blind ITT comparative study on 372 patients

R. Torta, C. Berra, R. Borio, L. Binaschi, A. Bovero, S.S. Racalbuto, E. Ramonda, I. Siri

Journal:

Journal of Psychosomatic Research

Year:

2006

Language:

english

File:

PDF, 42 KB

english, 2006

24

Induction of B1 bradykinin receptors in the kindled hippocampus increases extracellular glutamate levels: A microdialysis study

M. Mazzuferi, A. Binaschi, D. Rodi, S. Mantovani, M. Simonato

Journal:

Year:

2005

Language:

english

File:

PDF, 182 KB

english, 2005

25

A protein-mediated mechanism for the DNA sequence-specific action of topoisomerase II poisons

Giovanni Capranico, Monica Binaschi, M.Evelina Borgnetto, Franco Zunino, Manlio Palumbo

Journal:

Trends in Pharmacological Sciences

Year:

1997

Language:

english

File:

PDF, 184 KB

english, 1997

26

A protein-mediated mechanism for the DNA sequence-specific action of topoisomerase II poisons

Giovanni Capranico, Monica Binaschi, M.Evelina Borgnetto, Franco Zunino, Manlio Palumbo

Journal:

Trends in Pharmacological Sciences

Year:

1997

Language:

english

File:

PDF, 999 KB

english, 1997

27

Histone Deacetylase Inhibitors: From Bench to Clinic

Paris, Marielle, Porcelloni, Marina, Binaschi, Monica, Fattori, Daniela

Journal:

Journal of Medicinal Chemistry

Year:

2008

Language:

english

File:

PDF, 683 KB

english, 2008

28

Benzofused hydroxamic acids: Useful fragments for the preparation of histone deacetylase inhibitors. Part 1: Hit identification

Marastoni, Elena, Bartoli, Sandra, Berettoni, Marco, Cipollone, Amalia, Ettorre, Alessandro, Fincham, Christopher I., Mauro, Sandro, Paris, Marielle, Porcelloni, Marina, Bigioni, Mario, Binaschi, Moni

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2013

Language:

english

File:

PDF, 3.77 MB

english, 2013

29

Antiproliferative and Differentiating Activities of a Novel Series of Histone Deacetylase Inhibitors

Binaschi, Monica, Boldetti, Andrea, Gianni, Maurizio, Maggi, Carlo Alberto, Gensini, Martina, Bigioni, Mario, Parlani, Massimo, Giolitti, Alessandro, Fratelli, Maddalena, Valli, Claudia, Terao, Mineko

Journal:

ACS Medicinal Chemistry Letters

Year:

2010

Language:

english

File:

PDF, 1.40 MB

english, 2010

30

Impairment of GABA release in the hippocampus at the time of the first spontaneous seizure in the pilocarpine model of temporal lobe epilepsy

Soukupová, Marie, Binaschi, Anna, Falcicchia, Chiara, Zucchini, Silvia, Roncon, Paolo, Palma, Eleonora, Magri, Eros, Grandi, Enrico, Simonato, Michele

Journal:

Experimental Neurology

Year:

2014

Language:

english

File:

PDF, 2.04 MB

english, 2014

31

MicroRNA-130b Promotes Tumor Development and Is Associated with Poor Prognosis in Colorectal Cancer

Colangelo, Tommaso, Fucci, Alessandra, Votino, Carolina, Sabatino, Lina, Pancione, Massimo, Laudanna, Carmelo, Binaschi, Monica, Bigioni, Mario, Alberto Maggi, Carlo, Parente, Domenico, Forte, Nicola,

Journal:

Year:

2013

Language:

english

File:

PDF, 2.58 MB

english, 2013

32

Bradykinin B2 receptors increase hippocampal excitability and susceptibility to seizures in mice

Rodi, D., Buzzi, A., Barbieri, M., Zucchini, S., Verlengia, G., Binaschi, A., Regoli, D., Boschi, A., Ongali, B., Couture, R., Simonato, M.

Journal:

Year:

2013

Language:

english

File:

PDF, 1.12 MB

english, 2013

33

Histone Deacetylase Inhibitors: From Bench to Clinic

Paris, Marielle, Porcelloni, Marina, Binaschi, Monica, Fattori, Daniela

Journal:

Journal of Medicinal Chemistry

Year:

2008

File:

PDF, 18 KB

2008

34

Effects of Common Buffer Systems on Drug Activity: The Case of Clerocidin

Richter, Sara, Fabris, Daniele, Binaschi, Monica, Gatto, Barbara, Capranico, Giovanni, Palumbo, Manlio

Journal:

Chemical Research in Toxicology

Year:

2004

Language:

english

File:

PDF, 193 KB

english, 2004

35

Benzofused hydroxamic acids: Useful fragments for the preparation of histone deacetylase inhibitors. Part 2: 7-Fluorobenzothiophenes and benzofurans

Marastoni, Elena, Bartoli, Sandra, Berettoni, Marco, Cipollone, Amalia, Ettorre, Alessandro, Fincham, Christopher I., Mauro, Sandro, Paris, Marielle, Porcelloni, Marina, Bigioni, Mario, Binaschi, Moni

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2015

Language:

english

File:

PDF, 355 KB

english, 2015

36

Evaluation of the psychophysiological functions in humans exposed to the `Threshold Limit Value' of 1,1,1-trichloroethane

Salvini, M., Binaschi, S., Riva, M.

Journal:

Occupational and Environmental Medicine

Year:

1971

Language:

english

File:

PDF, 958 KB

english, 1971

37

FGF-2 Overexpression Increases Excitability and Seizure Susceptibility but Decreases Seizure-Induced Cell Loss

Zucchini, S., Buzzi, A., Barbieri, M., Rodi, D., Paradiso, B., Binaschi, A., Coffin, J. D., Marzola, A., Cifelli, P., Belluzzi, O., Simonato, M.

Journal:

Journal of Neuroscience

Year:

2008

Language:

english

File:

PDF, 645 KB

english, 2008

38

Evaluation of the psychophysiological functions in humans exposed to trichloroethylene

Salvini, M., Binaschi, S., Riva, M.

Journal:

Occupational and Environmental Medicine

Year:

1971

Language:

english

File:

PDF, 344 KB

english, 1971

39

On the Role of Somatostatin in Seizure Control: Clues from the Hippocampus

Binaschi, Anna, Bregola, Gianni, Simonato, Michele

Journal:

Reviews in the Neurosciences

Year:

2003

Language:

english

File:

PDF, 3.01 MB

english, 2003

40

Loss of drug-stimulated topoisomerase II DNA breaks in living cells is different at two unrelated loci

Journal:

Nucleic Acids Research

Year:

2000

Language:

english

File:

PDF, 434 KB

english, 2000

41

Localized delivery of fibroblast growth factor-2 and brain-derived neurotrophic factor reduces spontaneous seizures in an epilepsy model

Paradiso, B., Marconi, P., Zucchini, S., Berto, E., Binaschi, A., Bozac, A., Buzzi, A., Mazzuferi, M., Magri, E., Mora, G. N., Rodi, D., Su, T., Volpi, I., Zanetti, L., Marzola, A., Manservigi, R., Fa

Journal:

Proceedings of the National Academy of Sciences

Year:

2009

Language:

english

File:

PDF, 809 KB

english, 2009

42

Increased extracellular levels of glutamate in the hippocampus of chronically epileptic rats

Soukupova, M., Binaschi, A., Falcicchia, C., Palma, E., Roncon, P., Zucchini, S., Simonato, M.

Journal:

Year:

2015

Language:

english

File:

PDF, 827 KB

english, 2015

43

Characterization of a Topoisomerase II Gene Rearrangement in a Human Small-Cell Lung Cancer Cell Line

Binaschi, M., Giaccone, G., Gazdar, A. F., De Isabella, P., Ricotti, G. C. B. A., Capranico, G., Zunino, F.

Journal:

JNCI Journal of the National Cancer Institute

Year:

1992

File:

PDF, 2.29 MB

1992

44

Anthracyclines: Selected New Developments

Binaschi, M., Bigioni, M., Cipollone, A., Rossi, C., Goso, C., Maggi, C., Capranico, G., Animati, F.

Journal:

Current Medicinal Chemistry - Anti-Cancer Agents

Year:

2001

Language:

english

File:

PDF, 115 KB

english, 2001

45

Evaluation of the Psychophysiological Functions in Humans Exposed to the 'Threshold Limit Value' of 1,1,1-Trichloroethane

M. Salvini, S. Binaschi and M. Riva

Journal:

British Journal of Industrial Medicine

Year:

1971

Language:

english

File:

PDF, 1.02 MB

english, 1971

46

Proteomic screening identifies calreticulin as a miR-27a direct target repressing MHC class I cell surface exposure in colorectal cancer

Colangelo, T, Polcaro, G, Ziccardi, P, Pucci, B, Muccillo, L, Galgani, M, Fucci, A, Milone, M R, Budillon, A, Santopaolo, M, Votino, C, Pancione, M, Piepoli, A, Mazzoccoli, G, Binaschi, M, Bigioni, M,

Journal:

Cell Death and Disease

Year:

2016

Language:

english

File:

PDF, 4.05 MB

english, 2016

47

Delayed epileptogenesis in nociceptin/orphanin FQ-deficient mice

Binaschi, Anna, Zucchini, Silvia, Bregola, Gianni, Rodi, Donata, Mazzuferi, Manuela, Reinscheid, Rainer K., Simonato, Michele

Journal:

Year:

2003

Language:

english

File:

PDF, 114 KB

english, 2003

48

P71 INCREASED SUSCEPTIBILITY TO KAINATE SEIZURES AND DECREASED SEIZURE-INDUCED CELL LOSS IN TRANSGENIC MICE OVEREXPRESSING FIBROBLAST GROWTH FACTOR-2

Zucchini, S., Rodi, D., Paradiso, B., Binaschi, A., Grassi, C., Marzola, A., Coffin, J. D., Simonato, M.

Journal:

Behavioural Pharmacology

Year:

2004

Language:

english

File:

PDF, 63 KB

english, 2004

49

Kindled seizure-evoked somatostatin release in the hippocampus

Marti, Matteo, Bregola, Gianni, Binaschi, Anna, Gemignani, Anita, Simonato, Michele

Journal:

Year:

2000

Language:

english

File:

PDF, 128 KB

english, 2000

50

MEN15658: a new promising anti-tumoral drug active on resistant tumor cells

Salvatore, Carmela, Binaschi, Monica, Bigioni, Mario, Camarda, Grazia, Maggi, Carlo Alberto, Goso, Cristina

Journal:

Anti-Cancer Drugs

Year:

2004

Language:

english

File:

PDF, 193 KB

english, 2004

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